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U.S. News & World Report Neurology

Down Syndrome Center for Research and Treatment

Down syndrome is the most common genetic cause of learning disabilities in children. It occurs when an individual has three, rather than two, copies of chromosome 21. This additional genetic material alters the course of development and puts children with Down syndrome at risk for a number of health problems during childhood and later in life. People with Down syndrome typically also have mild to moderate cognitive impairment.

Family support and enrichment therapies make a big difference in the lives of both children and adults with Down syndrome. UC San Diego Down Syndrome Center for Research and Treatment is one of the first programs in the country to connect academic research with the treatment of Down syndrome for adults and children. The ultimate goal of our research is to cultivate treatments that enhance the lives of people with Down syndrome, making it possible for them to achieve more independence.

The Center partners with national and local patient advocacy organizations, community agencies and Rady Children’s Hospital to provide medical care, assessments and resources to children and adults with Down syndrome.


DS Action
DS Action holds monthly meetings in San Diego to identify the unmet needs of people with Down syndrome and to find creative solutions to meeting those needs. DS Action sponsors the pediatric Down Syndrome Center at Rady Children’s Hospital.

Down Syndrome Association of San Diego
Provides family support, education and advocacy to a thousand families and professionals in San Diego County. Affiliated with the National Down Syndrome Society, the National Down Syndrome Congress and the Exceptional Family Resource Center.

National Down Syndrome Society
The national advocate for people with Down syndrome with 350 affiliate groups. NDSS is one of the largest non-government supporters of Down syndrome research in the United States.

Visit the Down Syndrome Center for Treatment and Research for more resources.

UC San Diego Health System Links

School of Medicine Links

Down Syndrome Research

Discover clinical trials happening in the treatment of Down syndrome. 

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